| Serial No. | Name | From | To |
| 01- | Nawabzada Liaqat Ali Khan | 14 August 1947 | 16 October 1951 |
| 02- | Khawja Nazimuddin | 17 October 1951 | 17 April 1953 |
| 03- | Muhammad Ali Bogra | 17 April 1953 | 11 August 1955 |
| 04- | Chuhdary Muhammad Ali | 12 August 1955 | 12 September 1956 |
| 05- | Hussian Shaheed Suharwardi | 12 September 1956 | 16 October 1957 |
| 06- | Ibrahim Ismail Chundrigar | 17 October 1957 | 16 December 1957 |
| 07- | Malik Feroz Khan Noon | 16 December 1957 | 7 October 1958 |
| 08- | Muhammad Ayub Khan | 8 October 1958 | 27 October 1958 |
| 09- | Noor ul Amin  ( Nominated ) | 7 December 1971 | 20 December 1971 |
| 10- | Zulfiqar Ali Bhutto | 14 August 1973 | 5 July 1977 |
| 11- | Muhammad Khan Junejo | 23 March 1985 | 29 May 1988 |
| 12- | Benazir Bhutto | 2 December 1988 | 6 August 1990 |
| 13- | Ghulam Mustafa Jatoi (Caretaker) | 6 August 1990 | 6 November 1990 |
| 14- | Mian Muhamamd Nawaz Sharif | 6 November 1990 | 18 April 1993 |
| 15- | Mir Balakh Sher Mazari (Caretaker) | 18 April 1993 | 26 May 1993 |
| 14- | Mian Muhamamd Nawaz Sharif | 26 May 1993 | 18 July 1993 |
| 16- | Moin Ahmad Qureeshi (Caretaker) | 18 July 1993 | 19 October 1993 |
| 17- | Benazir Bhutto | 19 October 1993 | 5 November 1996 |
| 18- | Malik Meraj Khalid (Caretaker) | 5 November 1996 | 17 February 1997 |
| 19- | Muhamamd Nawaz Sharif | 17 February 1997 | 12 October 1999 |
| 20- | Zafarullah Khan Jamali | 21 November 2002 | 26 June 2004 |
| 21- | Chaudhry Shujaat Hussain | 30 June 2004 | 20 August 2004 |
| 22- | Shaukat Aziz | 29 August 2004 | 16 November 2007 |
| 23- | Muhammad Mian Soomro (Caretaker) | 16 November 2007 | 25 March 2008 |
| 24- | Syed Yousaf Raza Gillani | 25 March 2008 | 26 April 2012 |
| 25- | Raja Pervaiz Ashraf | 22 June 2012 | 25 March 2013 |
| 26- | Mir Hazar Khan Khoso (Caretaker) | 25 March 2013 | 5 June 2013 |
| 27- | Nawaz Sharif | 5 June 2013 | 28 July 2017 |
| 28- | Shahid Khaqan Abbasi | 1 August 2017 | 31 May 2018 |
| 29- | Imran Khan | 18 August 2018 | To till date |
